Searchable abstracts of presentations at key conferences on calcified tissues

ba0005p210 | Chondrocytes and cartilage | ECTS2016

Thyroid hormone locally interacts with the sympathetic nervous system to control bone linar growth

Miranda Rodrigues Manuela , Brum Patricia , de Azevedo Gouveia Cecilia Helena

It is well known that thyroid hormone (TH) is essential for normal bone growth and development. However, the mechanisms by which TH regulates these processes are poorly understood. Recently, the sympathetic nervous system (SNS) was identified as a potent regulator of bone metabolism. In vivo studies by our group have shown that TH interacts with the SNS to regulate bone mass and structure, and that this interaction involves α2 adrenoceptor (α2-A...